Animal models facilitate the study of the pathogenesis and complications of infectious disease, as well as allowing for the evaluation of treatment protocols that are not immediately feasible or ethical in human patients. Murine models provide populations of genetically uniform subjects that can be maintained under environmentally controlled conditions. Initial in vivo testing of new pharmaceutical agents in mouse models allows for critical early stage evaluation of potential toxicity and unexpected side effects of therapeutics prior to human application.

Our Animal Facilities and Technical Services Core offer the following services:

• Animal bio-safety level 2 and 3 suites
• Aerosol exposure and select agent capabilities
• Complex mouse surgery
• Production of hematopoietic chimeras
• Mouse rederivation and cryopreservation
• Contract breeding
• Mouse aging services

All animals are housed in individually ventilated micro isolator cages. More than 95 percent of the mice used each year are bred on site in the mouse breeding facility, which houses more than 100 inbred, congenic, transgenic, and mutant strains. A comprehensive sentinel monitoring program is in place for all animal facilities.

For more information, please contact:

William Reiley, Ph.D.
Senior CRO Program Manager
(518) 891-3080, ext. 315
TICRO@trudeauinstitute.org