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JR-SHIUAN LIN, PH.D.

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Jr-Shiuan Lin earned her B.S. in Zoology in 1998 from National Taiwan University in Taipei, Taiwan. She then received her Ph.D. in Immunology from the Graduate Institute of Immunology at National Taiwan University in 2005. While there, she worked in the lab of Dr. Betty Wu-Hsieh, investigating the roles of CD8 T cells, dendritic cells and macrophages in host defense against Histoplasma capsulatum, an intracellular fungal pathogen of macrophages. Dr. Lin remained in Dr. Wu-Hsieh’s lab as a postdoctoral fellow, where she continued her research until 2008.

Dr. Lin came to the Trudeau Institute in December 2008 as a postdoctoral fellow in the lab of Dr. Stephen Smiley. Working with Dr. Smiley, Dr. Lin established that T cell-mediated immunity suffices to combat Yersinia pestis, the etiologic agent of plague. She also identified the Y. pestis antigen that elicits protective CD8 T cell-mediated immune responses. Recently, Dr. Lin has established the fully virulent mouse model of pneumonic plague at the Trudeau Institute’s select agent suite.

Dr. Lin was promoted to Research Scientist in 2011 and then to an independent position as an Assistant Member of the faculty in December 2013. Her lab currently focuses on extending the research to the fully virulent strain of Y. pestis infection and how coagulation pathways impact immune defense against bacteria like Y. pestis.

To contact Dr. Lin email jslin@trudeauinstitute.org

Research Interests:
1. Immune defense against pneumonic plague.
2. Roles for blood clotting pathways during infection and immunity.
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ROBERT NORTH, PH.D. MARCIA A. BLACKMAN, PH.D. TIMOTHY SELLATI, PH.D. LAWRENCE L. JOHNSON, PH.D. ANDREA COOPER, PH.D. ELIZABETH LEADBETTER, PH.D. ALEXEI TUMANOV, M.D., PH.D. JR-SHIUAN LIN, PH.D. WILLIAM W. REILEY, PH.D. RON GOLDFARB, PH.D. SUSAN L. SWAIN, PH.D. RICHARD W. DUTTON, PH.D. DAVID WOODLAND, PH.D. GARY WINSLOW, PH.D. LAURA HAYNES, PH.D.